Introduction: Hippocampus is one of the major components of the brain, lies on ventral aspect of brain in temporal lobe of each cerebral hemisphere. It plays an important role in memory and therefore volumetric evaluation was done to establish normal values. The aim was to do a gender-wise comparison of right and left hippocampus volume in the age group of 21-40 years.

Materials and methods: Magnetic resonance imaging was done in 50 patients (20 females and 30 males) of age 21-40 years with complaint of epilepsy or headache. Magnetic resonance imaging was done in 50 patients (20 females and 30 males) of age 21-40 years with complaint of epilepsy or headache.

Results: Average of total volume of right side of hippocampus was 6.75 cm3 and of left side 6.21 cm3. In females, average volume of right hippocampus was 6.57 cm3 and left side 5.94 cm3. In males, average volume of right hippocampus was 6.88 cm3 while that of left was 6.37 cm3. Total average volume in females was 6.26 cm3 and in males was 6.62 cm3.

Conclusions: The total volume of right hippocampus was more than that of left side. The total average hippocampal volume of males was more than of females.

Keywords: Hippocampus, Volume, Brain, Magnetic resonance imaging